Join Waters in thinking outside the box for released N-glycan analysis
Bringing MS into Routine Monitoring with the ACQUITY QDa Detector
Greater confidence with mass confirmation of FLR peaks
Faster analysis with targeted MS profiling
Easily integrated with GMP-compliant workflows with Empower 3 Software
RapiFluor-MS labeled N-glycans monitored using an ACQUITY UPLC H-Class Bio System with detection by FLR and the ACQUITY QDa Detector, for confident assignment of known structures and mass data for unassigned structures.
Would you like mass information for your fluorescence peaks?
The Next Level of Characterization with Xevo G2-XS QTof MS
Easily and confidently assign low-level glycan components
Achieve unparalleled levels of MS and MS/MS performance by combining best-in-class technologies
Comparison of LC-MS chromatogram of 2AB-labeled N-glycans versus RapiFluor-MS-labeled N-glycans from the same mAb. 100 fold greater ESI+ MS response was observed for RapiFluor-MS-labeled sample. An MS spectrum (insert) shows the summed spectrum for a low abundance glycan within the sample.