Pittcon 2019

Philadelphia, Pennsylvania
March 17 – March 21

Featured products exhibited at Pittcon 2019.

BioAccord LC-MS System for Biopharmaceuticals

BioAccord LC-MS System for Biopharmaceuticals
The first SmartMS-enabled biopharmaceutical LC-MS solution
Purposefully designed for the analysis of biotherapeutic product attributes, with a small footprint, and SmartMS Technology, this system facilitates ease of deployment and ease of use, while delivering on industry demands for greater robustness and reproducibility.   Optimized results for proteins, peptides, and labeled released glycan are obtained with streamlined automated workflows integrating data acquisition, processing and reporting.  The BioAccord System platform is the ideal answer to the needs an industry looking to supplement or replace conventional low-information product assays with multi-attribute monitoring assays that facilitate speed to results and better decision making.  Compliance ready features ensure confidence in meeting regulatory requirements in later development and QC, and for harmonizing analytical and data platforms across the spectrum of biopharmaceutical development organizations.

www.waters.com/BioAccord

It’s your method. Shape its future.

Your analytical method faces many sources of variability over the course of its life. A new approach —  method lifecycle management —  helps you address risks at each phase of your method’s journey, resulting in more robust performance, lower costs, and ultimately, safer medicines. Come and learn what Waters is doing to help scientists understand how new USP and ICH guidelines will accelerate the adoption of a method lifecycle management approach.   Don’t miss our seminar on Wednesday March 20th.

ACQUITY UPLC H-Class PLUS System

Transform standard procedures into ultimate performance
Designed to support both HPLC and UPLC separations, the ACQUITY UPLC H-Class PLUS System delivers true UPLC performance, enables traditional HPLC separations, and provides a path to upgrade HPLC methods to UPLC when the time is right.  By scaling to UPLC, your laboratory will benefit from the combination of increased resolution, sensitivity, and speed that comes with modern small particle chemistries; and with the Waters’ Column Coach and Calculator, upgrading your method has never been easier.

For those developing new methods, the system’s versatility allows you to automatically screen important method parameters and discover the best set of chromatographic conditions for your sample, providing a more robust method and better results.  With up to six columns, each with independent temperature control, Auto-Blend Plus technology, up to 10 solvents online, and full support for peak tracking with the ACQUITY QDa Mass Detector, comprehensive method development workflows can be significantly accelerated and automated.

Whether your goal is to rapidly develop new methods, convert existing methods, or routinely analyze large numbers of incoming samples, the ACQUITY UPLC H-Class PLUS System can help reduce the time to result, while increasing the depth and quality of information received from your analysis. Because science never quits.

ACQUITY Advanced Polymer Characterization (APC) System

For High speed, high resolution analysis of low molecular weight polymers
The ACQUITY Advanced Polymer Characterization (APC) System, an ultra-high-performance size exclusion chromatography system, with a refractive index (RI) detector that has been optimized for low dispersion, is an ideal alternative to traditional technologies. The system uses rigid, sub-3-μm, ethyl bridge hybrid (BEH) particle columns that provide significant gains in stability and faster separations.

With APC, researchers can run diverse polymer applications on a single system, on one bank of columns using a variety of solvents. The system’s low overall dispersion can significantly improve analytical resolution, especially for low molecular weight oligomers.

www.waters.com/APC

UniSpray Ion Source

A novel ion source for ionization of a broader range of compounds
The unique geometry of the UniSpray ion source generates several different mechanisms to produce smaller droplets and enhance desolvation. These effects combine together to generate a greater number of free ions from the same amount of sample when compared to traditional ionization modes such as electrospray and typically results in an increase in response across a wide range of compounds.
The combination of a broader range of analytes and a potential boost in response give the possibility to consolidate several analysis methods into one, or even just remove the need to change over sources between analyses, saving you time and increasing your laboratory efficiency.

www.waters.com/unispray

BioResolve Columns for Biopharmaceuticals

Solutions that provide application-focused standards, methods, and exclusive support so you can easily and reliably achieve state-of-the-art separations. The BioResolve RP mAb Polyphenyl Columns are intended for reversed-phase analysis of intact or sub units of mAbs and ADCs using LC-UV and LC-MS; and the BioResolve SCX mAb Columns enable the characterization, monitoring, and QC of charge variants for mAb-based therapeutics during discovery, development, and manufacturing.

waters.com/BioResolve

VanGuard FIT (Fully Integrated Technology) Column Protection

Available with BioResolve SCX mAb Columns, this new column design combines two pieces into one.  Vanguard column protection prevents particulates and other contaminants from being carried onto the column, thereby extending its working life and reducing the cost-per-analysis without compromising the quality of the separation. Each batch of material used for the VanGuard FIT Cartridges is specifically quality control-tested with a new and commercially available mAb Charge Variant Standard derived from the National Institute of Science and Technology Reference Material 8671 (i.e. humanized IgG1κ) to help ensure batch-to-batch consistency of the new offering.

waters.com/BioResolve

Automation Partnership

Consumables purposefully designed for automation platforms to streamline complicated workflows. In collaboration with Andrew Alliance, Tecan, and Hamilton for the GlycoWorks RapiFluor-MS and ProteinWorks Kits, the offering includes valued support for automation in the form of detailed workstation layouts and base scripts for easy method implementation. In the booth, we will also feature the MPE2 from Hamilton which is compatible with all of Waters’ sample preparation plates and catridges (i.e., Oasis PRiME), making sample preparation even easier.

www.waters.com/automate

Empower 3 Software

Empower 3 Software, Waters’ flagship chromatography data software (CDS), makes it easier than ever to run samples and produce meaningful results without experiencing downtime for training, re-engineering workflow, or adding new software to support instruments or advanced chromatographic techniques.

Empower is the only cloud-deployable, compliance-ready enterprise CDS. Combining the worlds market leading chromatography data software with Amazon Web Services (AWS), the world’s most secure cloud services platform, Empower Cloud offers compute power, database storage, content delivery and other functionality to help businesses scale and grow. Empower Cloud leverages the internet to secure infrastructure technology, reducing the barriers of enterprise networks while helping to capture and grow new revenue and drive operational efficiency.

Designed to increase your productivity, improving how you collect, process and print chromatography data, Empower 3 continues to add customer driven improvements. These include Windows 10 support, new Empower Inventory Viewer, compliance enhancements, more compact LAC/E technology, wider applicability of Empower Mobile, and new Empower analytics for Data Integrity (EDS 365).

With developed electronic record compliance capabilities (following 21 CFR Part 11 and EU Annex 11, widely adopted by PIC/s countries), Empower 3 takes your ability to manage data integrity, advanced security features, and audit trails to new levels. Leverage electronic signatures to automate your laboratory workflow, and ease your mind regarding security, data integrity, and audits.

www.waters.com/empower

MassLynx

MassLynx Software increases the speed at which sample data is converted into valuable knowledge – acquire, analyze, manage, and share mass spectrometry information. MassLynx application managers streamline application-specific data processing.

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