Get PRiMED for the experience.

Oasis PRiME Product Family

Formats Available

5X Sample Concentration*

Reasons
You Need It
Introducing the Oasis PRiME Sample Preparation Family
The specificity of ion exchange for basic compounds achieved with a simple 3-step protocol.

Oasis PRiME MCX
The newest member of the PRiME Family with the specificity of mixed-mode/cation-eXchange
Why do 6 steps if you don’t have to?
Traditional Sample Prep

Condition

Equilibrate

Load

Wash

Wash

Elute
New 3-step protocol
Save valuable processing time and solvent costs with 50% fewer steps.
Oasis PRiME MCX
Catch and Release

Load
Plasma diluted 1:1 with a solution of 4% H3PO4 in 200 mM NH4HCO2

Wash
100% MeOH

Elute
MeOH with 5% NH4OH

99% Phospholipid Removal
Oasis PRiME HLB
Reversed-phase sample clean-up for routine analysis
3-step protocol
The fastest cleanup for acids, bases and neutrals.
Oasis PRiME HLB
Catch and Release

Load
Load pretreated samples

Wash
Wash 5% MeOH

Elute
Elute with 90/10 MeCN/MeOH

3-steps still too many?
Try the new 2-step protocol**.
Quickly removes matrix interferences.
Oasis PRiME HLB
Pass-through

Load
Pre-treated sample

Rinse (optional)
Collect hold-up volume

**Intended for high organic samples not requiring concentration and/or salt removal.
And it gets even SIMPLER…
Oasis Plus Short and Plus Light Cartridges connect directly to a syringe, no other equipment required.
Oasis PRiME HLB
Pass-through

Load
Pre-treated sample

Rinse (optional)
Collect hold-up volume

**Intended for high organic samples not requiring concentration and/or salt removal.
Featured Applications
Efficient Extraction of Quetiapine in Plasma Using Oasis PRiME MCX
Efficient and Clean Extraction of a Multi-Drug Panel with Oasis PRiME MCX for Clinical Research
Efficient Extraction of Propranolol, Doxepin and Loperamide in Plasma Using Oasis PRiME MCX
Development of Simple, Fast SPE Protocols for Basic Analyte Extraction with Phospholipid Removal Using Oasis PRiME MCX
Watch this video to learn how.
Let Oasis PRiME HLB Simplify SPE in your Laboratory.
7 Reasons you should use Oasis PRiME Sample Preparation Products
Only product of it’s kind.
Simple protocols with minimal processing steps.
Removes more than 95% of common matrix interferences.
High recoveries for a wide range of analytes.
Easy to implement without SPE expertise.
Faster flows with less plugging.
Oasis is the brand you can trust.
Waters has a long 40 year history of innovation in sample preparation

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